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CRBN 抗体 (AA 1-442)

This anti-CRBN antibody is a 小鼠 多克隆 antibody detecting CRBN in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN526543
发货至: 中国

Quick Overview for CRBN 抗体 (AA 1-442) (ABIN526543)

抗原

See all CRBN 抗体
CRBN (Cereblon (CRBN))

适用

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宿主

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小鼠

克隆类型

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多克隆

标记

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This CRBN antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-442

    原理

    Mouse polyclonal antibody raised against a full-length human CRBN protein.

    序列

    MAGEGDQQDA AHNMGNHLPL LPAESEEEDE MEVEDQDSKE AKKPNIINFD TSLPTSHTYL GADMEEFHGR TLHDDDSCQV IPVLPQVMMI LIPGQTLPLQ LFHPQEVSMV RNLIQKDRTF AVLAYSNVQE REAQFGTTAE IYAYREEQDF GIEIVKVKAI GRQRFKVLEL RTQSDGIQQA KVQILPECVL PSTMSAVQLE SLNKCQIFPS KPVSREDQCS YKWWQKYQKR KFHCANLTSW PRWLYSLYDA ETLMDRIKKQ LREWDENLKD DSLPSNPIDF SYRVAACLPI DDVLRIQLLK IGSAIQRLRC ELDIMNKCTS LCCKQCQETE ITTKNEIFSL SLCGPMAAYV NPHGYVHETL TVYKACNLNL IGRPSTEHSW FPGYAWTVAQ CKICASHIGW KFTATKKDMS PQKFWGLTRS ALLPTIPDTE DEISPDKVIL CL

    交叉反应

    产品特性

    Antibody reactive against mammalian transfected lysate.

    免疫原

    CRBN (NP_057386.2, 1 a.a. ~ 442 a.a) full-length human protein.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Peng, Li, Clarkson, Pehar, Lao, Hillmer, Barnhart, Christian, Mitchell, Bendlin, Sandor, Puglielli: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).

    Liu, Ye, Zou, Xu, Feng, Zou, Chen, Li, Cang: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, (2014) (PubMed).

    Charoenfuprasert, Yang, Lee, Chao, Chu, Lai, Hsu, Chang, Chen, Chen, Chang, Leu, Shih: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, (2011) (PubMed).

  • 抗原

    CRBN (Cereblon (CRBN))

    别名

    CRBN

    背景

    Full Gene Name: cereblon
    Synonyms: DKFZp781K0715,MGC27358,MRT2A

    基因ID

    51185

    NCBI登录号

    NM_016302
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