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BST2 抗体 (AA 1-180)

This 小鼠 多克隆 antibody specifically detects BST2 in WB, IF 和 IHC (p). It exhibits reactivity toward 人. It has been mentioned in 9+ publications
产品编号 ABIN513817
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BST2 抗体 (AA 1-180) (ABIN513817)

抗原

See all BST2 抗体
BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

适用

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宿主

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小鼠

克隆类型

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多克隆

标记

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This BST2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 1-180

    原理

    Mouse polyclonal antibody raised against a full-length human BST2 protein.

    序列

    MASTSYDYCR VPMEDGDKRC KLLLGIGILV LLIIVILGVP LIIFTIKANS EACRDGLRAV MECRNVTHLL QQELTEAQKG FQDVEAQAAT CNHTVMALMA SLDAEKAQGQ KKVEELEGEI TTLNHKLQDA SAEVERLRRE NQVLSVRIAD KKYYPSSQDS SSAAAPQLLI VLLGLSALLQ

    交叉反应

    产品特性

    Antibody reactive against mammalian transfected lysate.

    免疫原

    BST2 (NP_004326.1, 1 a.a. ~ 180 a.a) full-length human protein.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Edgar, Manna, Nishimura, Banting, Robinson: "Tetherin is an exosomal tether." in: eLife, Vol. 5, (2016) (PubMed).

    Brinkmann, Nehlmeier, Walendy-Gnirß, Nehls, González Hernández, Hoffmann, Qiu, Takada, Schindler, Pöhlmann: "The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies." in: Journal of virology, Vol. 90, Issue 24, pp. 11075-11086, (2016) (PubMed).

    Yang, Lopez, Exline, Haworth, Cannon: "Lack of adaptation to human tetherin in HIV-1 group O and P." in: Retrovirology, Vol. 8, pp. 78, (2011) (PubMed).

    Gupta, Mlcochova, Pelchen-Matthews, Petit, Mattiuzzo, Pillay, Takeuchi, Marsh, Towers: "Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20889-94, (2010) (PubMed).

    Hauser, Lopez, Yang, Oldenburg, Exline, Guatelli, Cannon: "HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment." in: Retrovirology, Vol. 7, pp. 51, (2010) (PubMed).

    Casartelli, Sourisseau, Feldmann, Guivel-Benhassine, Mallet, Marcelin, Guatelli, Schwartz: "Tetherin restricts productive HIV-1 cell-to-cell transmission." in: PLoS pathogens, Vol. 6, Issue 6, pp. e1000955, (2010) (PubMed).

    Karetnikov, Suomalainen: "Tethered virions are intermediates in the assembly and release of HIV-1 particles." in: Virology, Vol. 407, Issue 2, pp. 289-95, (2010) (PubMed).

    Lopez, Yang, Hauser, Exline, Haworth, Oldenburg, Cannon: "Ebola virus glycoprotein counteracts BST-2/Tetherin restriction in a sequence-independent manner that does not require tetherin surface removal." in: Journal of virology, Vol. 84, Issue 14, pp. 7243-55, (2010) (PubMed).

    Iwabu, Fujita, Kinomoto, Kaneko, Ishizaka, Tanaka, Sata, Tokunaga: "HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 35060-72, (2009) (PubMed).

  • 抗原

    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

    别名

    BST2

    背景

    Full Gene Name: bone marrow stromal cell antigen 2
    Synonyms: CD317

    基因ID

    684

    NCBI登录号

    NM_004335

    途径

    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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