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14-3-3 theta 抗体

The 大鼠 单克隆 anti-14-3-3 theta antibody (Clone ABM52H6) (ABIN5027747) specifically detects 14-3-3 theta in WB. The antibody is reactive with 小鼠 samples.
产品编号 ABIN5027747
发货至: 中国
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Quick Overview for 14-3-3 theta 抗体 (ABIN5027747)

抗原

See all 14-3-3 theta (YWHAQ) 抗体
14-3-3 theta (YWHAQ)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This 14-3-3 theta antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

ABM52H6
  • 纯化方法

    Protein G Chromatography

    免疫原

    Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.

    亚型

    IgG2a kappa
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    14-3-3 theta (YWHAQ)

    别名

    14-3-3 Theta

    背景

    14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.

    分子量

    27 kDa

    基因ID

    10971

    UniProt

    P27348

    途径

    Apoptosis, Myometrial Relaxation and Contraction
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