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CCR6 抗体

This anti-CCR6 antibody is a 大鼠 单克隆 antibody detecting CCR6 in WB. Suitable for 小鼠.
产品编号 ABIN5027745
发货至: 中国

Quick Overview for CCR6 抗体 (ABIN5027745)

抗原

See all CCR6 抗体
CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

适用

  • 64
  • 15
  • 13
  • 3
  • 1
小鼠

宿主

  • 47
  • 14
  • 3
  • 1
  • 1
大鼠

克隆类型

  • 46
  • 17
  • 2
单克隆

标记

  • 37
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCR6 antibody is un-conjugated

应用范围

  • 29
  • 22
  • 16
  • 15
  • 12
  • 7
  • 2
Western Blotting (WB)

克隆位点

ABM40H1
  • 纯化方法

    Protein G Chromatography

    免疫原

    Full length recombinant protein from mCD196 was used as the immunogen for this antibody.

    亚型

    IgG2a kappa
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

    别名

    mCD196

    背景

    CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naï,ve T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.

    分子量

    47 kDa

    基因ID

    1235

    UniProt

    P51684

    途径

    cAMP Metabolic Process
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