CCR6 抗体
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北京 101111
Quick Overview for CCR6 抗体 (ABIN5027745)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G Chromatography
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免疫原
- Full length recombinant protein from mCD196 was used as the immunogen for this antibody.
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亚型
- IgG2a kappa
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anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibody
CCR6 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 7C6D9 unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 201-300) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (C-Term) antibodyCCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 322-374) antibodyCCR6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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别名
- mCD196
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背景
- CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naï,ve T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.
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分子量
- 47 kDa
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基因ID
- 1235
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UniProt
- P51684
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途径
- cAMP Metabolic Process
抗原
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