UNC93B1 抗体 (AA 300-597)
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北京 101111
Quick Overview for UNC93B1 抗体 (AA 300-597) (ABIN5027623)
抗原
See all UNC93B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-597
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 4-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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别名
- UNC93B
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背景
- Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.
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分子量
- 70 kDa
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基因ID
- 81622
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UniProt
- Q9H1C4
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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