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TFG 抗体 (AA 196-400)

TFG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027601
发货至: 中国
  • 抗原 See all TFG 抗体
    TFG (Trk-Fused Gene (TFG))
    抗原表位
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 196-400
    适用
    • 51
    • 14
    • 9
    宿主
    • 44
    • 7
    克隆类型
    • 37
    • 14
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFG antibody is un-conjugated
    应用范围
    • 43
    • 27
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant TRK Fused gene protein (amino acids 196-400) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product TFG Primary Antibody
  • 应用备注
    WB:1-2 μg/mL, IHC: 20 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    TFG (Trk-Fused Gene (TFG))
    别名
    TRK Fused gene (TFG 产品)
    别名
    wu:fb11c10 antibody, zgc:55342 antibody, zgc:77230 antibody, HMSNP antibody, SPG57 antibody, TF6 antibody, TRKT3 antibody, AI173908 antibody, trk-fused gene antibody, TRK-fused gene antibody, Trk-fused gene antibody, tfg antibody, TFG antibody, Tfg antibody
    背景
    TRK Fused gene (TFG) encodes a protein that plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules. It is a conserved regulator of protein secretion that assembles into an oligomeric matrix at the interface between the ER and ER Golgi intermediate compartments in metazoans cells. Originally TFG was identified as a fusion partner of the NTRK1 gene in human papillary thyroid carcinoma. It is also involved in another chromosome translocation with the ALK gene in anaplastic large-cell lymphomas. It is located on the q arm of human chromosome 3 and encodes a ubiquitously expressed cytoplasmic protein. Structural analysis reveals TFG containing a coiled-coil (CC) domain and a serine, proline, tyrosine, glycine and glutamine (SPYGQ)-rich region. Interestingly, the TFG protein interacts with the NF-kappaB essential modulator and TRAF family member-associated NF-kappaB activator proteins, suggesting that it may play a key role in NF-kappaB regulation.
    分子量
    50 kDa
    基因ID
    10342
    UniProt
    Q92734
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