TFG 抗体 (AA 196-400)
Quick Overview for TFG 抗体 (AA 196-400) (ABIN5027601)
抗原
See all TFG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 196-400
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant TRK Fused gene protein (amino acids 196-400) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Trk-Fused Gene (TFG) (AA 1-240) antibody
TFG 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Trk-Fused Gene (TFG) (AA 1-400) antibodyTFG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Trk-Fused Gene (TFG) (AA 1-110) antibodyTFG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Trk-Fused Gene (TFG) antibodyTFG 适用: 人 WB, IP, ICC 宿主: 小鼠 Monoclonal TFG-03 unconjugated
anti-Trk-Fused Gene (TFG) (AA 1-240) antibodyTFG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1-2 μg/mL, IHC: 20 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TFG (Trk-Fused Gene (TFG))
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别名
- TRK Fused gene
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背景
- TRK Fused gene (TFG) encodes a protein that plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules. It is a conserved regulator of protein secretion that assembles into an oligomeric matrix at the interface between the ER and ER Golgi intermediate compartments in metazoans cells. Originally TFG was identified as a fusion partner of the NTRK1 gene in human papillary thyroid carcinoma. It is also involved in another chromosome translocation with the ALK gene in anaplastic large-cell lymphomas. It is located on the q arm of human chromosome 3 and encodes a ubiquitously expressed cytoplasmic protein. Structural analysis reveals TFG containing a coiled-coil (CC) domain and a serine, proline, tyrosine, glycine and glutamine (SPYGQ)-rich region. Interestingly, the TFG protein interacts with the NF-kappaB essential modulator and TRAF family member-associated NF-kappaB activator proteins, suggesting that it may play a key role in NF-kappaB regulation.
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分子量
- 50 kDa
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基因ID
- 10342
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UniProt
- Q92734
抗原
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