TLR10 抗体 (AA 100-369)
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- 抗原 See all TLR10 抗体
- TLR10 (Toll-Like Receptor 10 (TLR10))
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抗原表位
- AA 100-369
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A partial length recombinant TLR10 protein (amino acids 100-369) was used as the immunogen for this antibody.
- 克隆位点
- ABM3C85
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TLR10 Primary Antibody
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anti-Toll-Like Receptor 10 (TLR10) (AA 1-811) antibody
TLR10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Toll-Like Receptor 10 (TLR10) (AA 20-250) antibodyTLR10 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 10 (TLR10) (AA 617-784) antibodyTLR10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 2-4 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- TLR10 (Toll-Like Receptor 10 (TLR10))
- 别名
- TLR10 (TLR10 产品)
- 别名
- TLR10 antibody, CD290 antibody, toll like receptor 10 antibody, toll-like receptor 10 antibody, TLR10 antibody, Tlr10 antibody
- 背景
- TLR10 (Toll-Like Receptor10) is an orphan member of the TLR family and is the only pattern-recognition receptor without known ligand specificity and biological function. This protein plays a role in innate immune responses following viral infection. Influenza virus infection increased TLR10 expression and TLR10 contributed to innate immune sensing of viral infection leading to cytokine induction, including proinflammatory cytokines and interferons. Blocking TLR10 by antagonistic antibodies enhanced proinflammatory cytokine production, including IL-1Beta, specifically after exposure to TLR2 ligands. TLR10 is in a locus that also contains TLR1 and TLR6, two receptors known to function as coreceptors for TLR2. TLR10 is predominantly expressed in tissues rich in immune cells, such as spleen, lymph node, thymus, tonsil, and lung. Expression of TLR10 can be induced in B cells, dendritic cells, eosinophils, and neutrophils, as well as on nonimmune cells, such as trophoblasts.
- 分子量
- 116 kDa
- 基因ID
- 81793
- UniProt
- Q9BXR5
- 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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