TLR1 抗体 (AA 300-500)
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北京 101111
Quick Overview for TLR1 抗体 (AA 300-500) (ABIN5027567)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-500
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交叉反应
- 小鼠
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 4-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TLR1 (Toll-Like Receptor 1 (TLR1))
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别名
- TLR1
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背景
- Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
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分子量
- 110 kDa
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基因ID
- 7096
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UniProt
- Q15399
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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