KAT5 抗体 (AA 300-500)
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北京 101111
Quick Overview for KAT5 抗体 (AA 300-500) (ABIN5027563)
抗原
See all KAT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-500
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant TIP60 protein (amino acids 300-500) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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别名
- TIP60
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背景
- TIP60 (60 kDa Tat-interactive protein) alternatively called as Lysine acetyltransferase 5 (KAT5) or Histone acetyltransferase KAT5 is a member of MYST protein family with four isoforms (58, 53, 61 and 56 kDa). TIP60 plays important roles in regulating chromatin remodeling, transcription, DNA repair and apoptosis. TIP60 causes transcription activation by acetylating nucleosomal histones H4 and H2A. Mutations at gene level are associated with diseases like HIV-1, and Kaposis sarcoma. TIP60 is mainly expressed in brain tissue.
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分子量
- 55 kDa
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基因ID
- 10524
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UniProt
- Q92993
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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