RAGE 抗体 (AA 1-280)
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Quick Overview for RAGE 抗体 (AA 1-280) (ABIN5027503)
抗原
See all RAGE (AGER) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-280
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant RAGE protein (amino acids 1-280) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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别名
- RAGE
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背景
- RAGE (Advanced glycosylation end product-specific receptor) is a member of immunoglobulin superfamily with multiple isoforms being located on the membrane of endothelial cells. RAGE acts transporter of amyloid beta peptide across the blood brain barrier. It has also been reported that RAGE is overexpressed in Alzheimer disease. RAGE is also involved in vascular inflammation in atherosclerosis, type 2 diabetes mellitus. High levels of RAGE protein is found in brain tissue.
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分子量
- 42 kDa
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基因ID
- 177
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UniProt
- Q15109
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途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
抗原
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