Dnmt2 抗体
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北京 101111
Quick Overview for Dnmt2 抗体 (ABIN5027475)
抗原
See all Dnmt2 (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鼠
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant protein from DNMT2 was used as the immunogen for this antibody.
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亚型
- IgG1 kappa
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应用备注
- WB: 4-6 μg/mL, FACS: 0.5-1 μg/10^6
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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别名
- DNMT2
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背景
- DNMT2, also known as tRNA-aspartic acid methyltransferase 1 (TRDMT1), is highly conserved cytosine-C5 methyltransferase that introduces the C38 methylation of tRNAAsp in many species, including lower eukaryotes, plants, insects, and humans. DNMT2 contains all 10 sequence motifs that are conserved among m5C MTases, including the consensus S-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide. It is a relatively small protein of 391 amino acids and lacks the large N-terminal domains present in the DNMT1 and DNMT3 families. DNMT2 is ubiquitously expressed with multiple mRNA species in most human and mouse adult tissues. It is variably expressed in human cancer cell lines.
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分子量
- 45 kDa
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基因ID
- 1787
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UniProt
- Q6ICS7
抗原
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