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PD-L1 抗体 (AA 18-227)

The 小鼠单克隆 anti-PD-L1 antibody is suitable to detect PD-L1 in samples from 人. It has been validated for WB, FACS 和 IHC.

FACS

1 image

产品编号 ABIN5027434

发货至: 中国

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Quick Overview for PD-L1 抗体 (AA 18-227) (ABIN5027434)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This PD-L1 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

ABM4E54

Discover our top product PD-L1 Primary Antibody

抗原表位
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1
AA 18-227

纯化方法

Protein G Chromatography

免疫原

A partial length recombinant PDL1 protein (amino acids 18-227) was used as the immunogen for this antibody.

亚型

IgG2a kappa
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) antibody
PD-L1 适用: 人 IHC 宿主: 兔 Monoclonal 711R unconjugated Recombinant Antibody

应用备注

WB: 0.5-1 μg/mL, IHC-5-10 μg/mL, FACS: 1-2 μg/mL

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

PBS containing 0.05 % BSA, PH 7.4

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
抗原

PD-L1 (CD274 (PD-L1))

别名

PDL1

背景

PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases.

分子量

19 kDa

基因ID

29126

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints