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PD-L1 抗体 (AA 18-227)

This anti-PD-L1 antibody is a 兔多克隆 antibody detecting PD-L1 in WB. Suitable for 人.

Image no. 1 for anti-CD274 (PD-L1) (AA 18-227) antibody (ABIN5027432) (PD-L1 抗体 (AA 18-227))

1 image

产品编号 ABIN5027432

发货至: 中国

Quick Overview for PD-L1 抗体 (AA 18-227) (ABIN5027432)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

212
139
65
6
6
5
5
1
1

人

宿主

135
93
20
5
4
4
2
1

兔

克隆类型

多克隆

标记

This PD-L1 antibody is un-conjugated

应用范围

165
136
66
63
40
34
28
22
22
14
11
9
7
7
5
3
3
2
2
1
1
1
1
1
1
1
1

Western Blotting (WB)

Discover our top product PD-L1 Primary Antibody

抗原表位
31

29

16

15

10

9

7

7

7

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 18-227

纯化方法

Protein A Chromatography

免疫原

A partial length recombinant PDL1 protein (amino acids 18-227) was used as the immunogen for this antibody.

亚型

IgG
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 2-4 μg/mL

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

PBS containing 0.05 % BSA, PH 7.4

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
抗原

PD-L1 (CD274 (PD-L1))

别名

PD-L1 / CD274

背景

Programmed death ligand 1/PD-L1 (also called B7-H1 and CD274) is a T cell inhibitory molecule that is expressed on antigen presenting cells (APC) leading to T cell anergy and/or apoptosis upon ligation to its receptor Programmed death-1 (PD-1, CD279) on T cells. PD-L1 is expressed on tumor cells of a subset of breast cancer patients. It could also induce EMT and enhance RCC cell cancer stemness through up-regulation of SREBP-1c. Blocking the immunosuppressive PD-1/PD-L1 pathway has antitumor activity in multiple cancer types, and PD-L1 expression on tumor cells and infiltrating myeloid cells correlates with the likelihood of response.

分子量

33 kDa

基因ID

29126

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints

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