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PAPPA 抗体 (AA 332-561)

PAPPA 适用: 人 IHC 宿主: 小鼠 Monoclonal ABM4C62 unconjugated
产品编号 ABIN5027424
发货至: 中国
  • 抗原 See all PAPPA 抗体
    PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
    抗原表位
    • 15
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 332-561
    适用
    • 79
    • 23
    宿主
    • 45
    • 39
    • 1
    小鼠
    克隆类型
    • 46
    • 39
    单克隆
    标记
    • 32
    • 13
    • 11
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAPPA antibody is un-conjugated
    应用范围
    • 48
    • 45
    • 27
    • 17
    • 13
    • 13
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant PAPP-A protein (amino acids 332-561) was used as the immunogen for this antibody.
    克隆位点
    ABM4C62
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PAPPA Primary Antibody
  • 应用备注
    IHC: 5-10 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
    别名
    PAPP-A (PAPPA 产品)
    别名
    8430414N03Rik antibody, IGFBP-4ase antibody, PAG1 antibody, PAPP-A antibody, ASBABP2 antibody, DIPLA1 antibody, PAPA antibody, PAPPA1 antibody, Pappa antibody, pappalysin 1 antibody, pregnancy-associated plasma protein A antibody, PAPPA antibody, Pappa antibody, Pappa1 antibody
    背景
    PAPP-A (pregnancy-associated plasma protein A) is a zinc metalloproteinase in the insulin-like growth factor system that is expressed by tissues outside of pregnancy and involved in normal and dysregulated growth. It has prognostic impact in pregnancy and acute coronary syndrome. PAPP-A regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. PAPP-A levels is associated with abnormal glucose metabolism and increased risk of atherosclerosis in AGHD (Adult Growth Hormone Deficiency) patients.
    基因ID
    60676
    UniProt
    Q9BXP8
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