MLH1 抗体 (AA 289-492)
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Quick Overview for MLH1 抗体 (AA 289-492) (ABIN5027360)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 289-492
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant MLH1 protein (amino acids 289-492) was used as the immunogen for this antibody.
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亚型
- IgG2b
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应用备注
- IHC: 5-10 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
- MutL homolog 1 (MLH1) is a member of mismatch repair genes (MMR) that plays a crucial role in correcting replication errors, cell cycle arrest, apoptosis and oxidative stress. MLH1 is a human homolog of the E.coli DNA mismatch repair gene. It mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Diseases associated with MLH1 include colorectal cancer, hereditary nonpolyposis, type 2 and lynch syndrome.
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基因ID
- 4292
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UniProt
- P40692
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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