HOXA9 抗体 (AA 63-272)
Quick Overview for HOXA9 抗体 (AA 63-272) (ABIN5027256)
抗原
See all HOXA9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-272
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- HOXA9 (Homeobox A9 (HOXA9))
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别名
- HOXA9
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背景
- HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.
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分子量
- 30 kDa
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基因ID
- 3205
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UniProt
- P31269
抗原
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