FURIN 抗体 (AA 602-791)
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北京 101111
Quick Overview for FURIN 抗体 (AA 602-791) (ABIN5027210)
抗原
See all FURIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 602-791
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Furin protein (amino acids 602-791) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 120-370) antibody
FURIN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 587-748) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 418-573) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (Internal Region) antibodyVerified FURIN 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 385-500) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 578-734) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 520-701) antibodyFURIN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1C3 unconjugated Recombinant Antibody
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 105-221) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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别名
- Furin
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背景
- Furin is a member of the PCs family (Pro-Hormone/Pro-Protein Convertase) of subtilisin-like endoproteinases. Furin along with PCs are intensively investigated as pharmacological targets for the treatment of many diseases, e.g., atherosclerosis, hypercholesterolaemia, and cancer, as well as viral and bacterial infections. Furin has been implicated in processing the Env (Envelope) proteins of human endogenous retroviruses, syncytins, the only possible fusogens known to be involved in placenta syncytialization, and therefore may participate in syncytin-mediated cell fusion in cells of both trophoblast and non-trophoblast lineages. Furin catalyzes proteolytic maturation of a diverse repertoire of growth factors, receptors, and enzyme precursors within multiple secretory pathway compartments. Proteolysis by furin is highly specific and occurs at C-terminal to a multibasic recognition motive. Furin is highly expressed in EVTs (Extravillous CTBs) and that furin function is required for trophoblast cell invasion into the maternal endometrium.
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分子量
- 97 kDa
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基因ID
- 5045
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UniProt
- P09958
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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