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DEPTOR 抗体 (AA 111-301)
DEPTOR
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
DEPTOR抗体详情
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抗原
See all DEPTOR 抗体
DEPTOR
(DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
抗原表位
All epitopes for DEPTOR 抗体
AA 111-301
适用
All reactivities for DEPTOR 抗体
人
宿主
All hosts for DEPTOR 抗体
兔
克隆类型
All clonalities for DEPTOR 抗体
多克隆
标记
All conjugates for DEPTOR 抗体
This DEPTOR antibody is un-conjugated
应用范围
All applications for DEPTOR 抗体
Western Blotting (WB)
纯化方法
Protein A Chromatography
免疫原
A partial length recombinant DEPTOR protein (amino acids 111-301) was used as the immunogen for this antibody.
亚型
IgG
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Discover our top product DEPTOR Primary Antibody
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使用细节
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应用备注
WB: 2-4 μg/mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
PBS containing 0.05 % BSA, PH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
DEPTOR目标详情
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抗原
DEPTOR
(DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
别名
DEPTOR/DEPDC6 (DEPTOR 产品 )
别名
DEP.6 antibody, DEPDC6 antibody, 4731402B04Rik antibody, 9130412E02Rik antibody, D15Ertd336e antibody, D15Ertd597e antibody, Depdc6 antibody, Depdc6-001 antibody, Depdc6-002 antibody, R75183 antibody, mKIAA4200 antibody, RGD1561030 antibody, RAPGEF4 antibody, DEP domain containing MTOR interacting protein antibody, DEP domain containing MTOR-interacting protein antibody, DEPTOR antibody, Deptor antibody
背景
DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
分子量
46 kDa
基因ID
64798
UniProt
Q8TB45
途径
PI3K-Akt Signaling , RTK signaling , Regulation of Cell Size , BCR Signaling , Warburg Effect
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