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DEPTOR 抗体 (AA 111-301)

DEPTOR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027150
发货至: 中国
  • 抗原 See all DEPTOR 抗体
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    抗原表位
    • 15
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-301
    适用
    • 46
    • 34
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 41
    • 4
    • 1
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DEPTOR antibody is un-conjugated
    应用范围
    • 44
    • 26
    • 26
    • 10
    • 8
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant DEPTOR protein (amino acids 111-301) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product DEPTOR Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    别名
    DEPTOR/DEPDC6 (DEPTOR 产品)
    别名
    DEP.6 antibody, DEPDC6 antibody, 4731402B04Rik antibody, 9130412E02Rik antibody, D15Ertd336e antibody, D15Ertd597e antibody, Depdc6 antibody, Depdc6-001 antibody, Depdc6-002 antibody, R75183 antibody, mKIAA4200 antibody, RGD1561030 antibody, RAPGEF4 antibody, DEP domain containing MTOR interacting protein antibody, DEP domain containing MTOR-interacting protein antibody, DEPTOR antibody, Deptor antibody
    背景
    DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
    分子量
    46 kDa
    基因ID
    64798
    UniProt
    Q8TB45
    途径
    PI3K-Akt Signaling, RTK signaling, Regulation of Cell Size, BCR Signaling, Warburg Effect
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