DEPTOR 抗体 (AA 111-301)
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北京 101111
Quick Overview for DEPTOR 抗体 (AA 111-301) (ABIN5027150)
抗原
See all DEPTOR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-301
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant DEPTOR protein (amino acids 111-301) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 56-170) antibody
DEPTOR 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 86-120) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal RB57442 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 3-38) antibodyDEPTOR 适用: 人 WB 宿主: 兔 Polyclonal RB57441 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 230-280) antibodyDEPTOR 适用: 人, 大鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
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别名
- DEPTOR/DEPDC6
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背景
- DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
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分子量
- 46 kDa
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基因ID
- 64798
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UniProt
- Q8TB45
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途径
- PI3K-Akt Signaling, RTK signaling, Regulation of Cell Size, BCR Signaling, Warburg Effect
抗原
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