DLL3 抗体 (AA 62-286)
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北京 101111
Quick Overview for DLL3 抗体 (AA 62-286) (ABIN5027148)
抗原
See all DLL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 62-286
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DLL3 (delta Like Protein 3 (DLL3))
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别名
- Delta like 3
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背景
- Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.
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分子量
- 65 kDa
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基因ID
- 10683
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UniProt
- Q9NYJ7
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途径
- Notch Signaling
抗原
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