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CD33 抗体 (AA 28-320)

This 小鼠 单克隆 antibody specifically detects CD33 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN5027091
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD33 抗体 (AA 28-320) (ABIN5027091)

抗原

See all CD33 抗体
CD33

适用

  • 218
  • 36
  • 16
  • 13
  • 7
  • 6
  • 3
  • 1
  • 1

宿主

  • 112
  • 99
  • 15
  • 1
小鼠

克隆类型

  • 132
  • 94
  • 1
单克隆

标记

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  • 9
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  • 2
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  • 1
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  • 1
  • 1
  • 1
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This CD33 antibody is un-conjugated

应用范围

  • 127
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

ABM29D3
  • 抗原表位

    • 16
    • 16
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-320

    纯化方法

    Protein G Chromatography

    免疫原

    A partial length recombinant CD33 protein (amino acids 28-320) was used as the immunogen for this antibody.

    亚型

    IgG2a kappa
  • 应用备注

    WB: 2-4 μg/mL, IHC: 5 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    CD33

    别名

    CD33

    背景

    CD33 is a member of the SIGLEC (Sialic Acid-Binding Ig-Like Lectin) family of receptors, and the gene comprises seven coding exons. Exon 2 encodes the canonical IgV domain, exon 4 encodes the IgC structural domain, and exons 6 and 7 encode cytosolic ITIMs (Immunotyrosine Inhibitory Motifs). CD33 acts as a cell surface antigen which is expressed on normal myeloid cells and CD34+ blasts in AML (Acute Myeloid Leukemia). The antigen serves as a target of GO (Gemtuzumab/Ozogamicin), which exerts anti-leukemic effects in refractory AML.

    分子量

    39 kDa

    基因ID

    945

    UniProt

    P20138
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