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MME 抗体 (AA 282-496)

This anti-MME antibody is a 小鼠单克隆 antibody detecting MME in WB 和 IHC. Suitable for 人.

Immunohistochemistry (IHC) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 282-496) antibody (ABIN5027077) (MME 抗体 (AA 282-496))

1 image

产品编号 ABIN5027077

发货至: 中国

Quick Overview for MME 抗体 (AA 282-496) (ABIN5027077)

抗原

See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))

适用

229
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41
3
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人

宿主

小鼠

克隆类型

单克隆

标记

This MME antibody is un-conjugated

应用范围

138
116
81
58
40
37
33
26
19
10
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5
5
3
2
2
1
1
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

ABM4A52

Discover our top product MME Primary Antibody

抗原表位
36

12

10

8

8

7

6

6

5

4

4

3

3

3

2

2

2

2

2

2

2

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1

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1

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1

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1
AA 282-496

纯化方法

Protein G Chromatography

免疫原

A partial length recombinant CD10 protein (amino acids 282-496) was used as the immunogen for this antibody.

亚型

IgG2b kappa
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
MME 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
MME 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3G6B11 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6G12E12 unconjugated

应用备注

WB: 0.5-1 μg/mL, IHC: 5-10 μg/mL

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

PBS containing 0.05 % BSA, PH 7.4

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

CD10

物质类

Chemical

背景

CD10, also known as membrane metalloendopeptidase, neutral endopeptidase, neprilysin and common acute lymphoblastic leukaemia antigen (CALLA), is a zinc-dependent metalloendoprotease that cleaves signaling peptides. It is widely expressed in various normal tissues and in epithelial, stromal or both components of various malignancies. CD10 is a marker for intestinal epithelial brush border. It is also present in normal bile ducts and gallbladder epithelia but is absent in cholangiocarcinomas. It is con-sidered as the prototype of this family of membrane-bound, zinc-dependent endopeptidases, which regulate the physiological action of various peptides by lowering their extracellular concentration available for receptor binding. CD10 is also known to be an amyloid b-peptide (Ab) degrading enzyme. Polymorphisms in the CD10 gene increase the risk for Alzheimer disease. Outside the nervous system, it is present on the surface of neutrophils and regulates their activation by degradation of in ammatory peptides.

分子量

97 kDa

基因ID

4311

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

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