ATG16L1 抗体 (AA 35-260)
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北京 101111
Quick Overview for ATG16L1 抗体 (AA 35-260) (ABIN5027029)
抗原
See all ATG16L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-260
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant APG16L protein (amino acids 35-260) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 200-300) antibody
ATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 342-607) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 1-284) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5H9A11 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 161-190) antibodyATG16L1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB07490 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 84-114) antibodyATG16L1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 501-607) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F8C2 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
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别名
- APG16L
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背景
- ATG16L1/APG16L is part of a large protein complex that functions as a molecular scaffold mediating protein-protein interactions necessary for formation of the autophagosome in response to both classical and pathogen-related autophagy stimuli. APG16L protein contains an N-terminal Atg5-binding domain, a coiled-coil domain and a C-terminal WD (tryptophan-aspartic acid)-repeat domain. APG16L forms a complex with the Atg12 Atg5 conjugate and together they are actively translocated to the phagophore and are further elongated during autophagosome formation. Genetic variation in the APG16L gene has been recently implicated in Crohn's disease pathogenesis. Polymorphism within APG16L gene results in excessive production of IL-1beta and IL-6 culmunating in the inflammatory process in Crohn's disease.
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分子量
- 53 kDa (Isoform)
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基因ID
- 55054
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UniProt
- Q676U5
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途径
- Autophagy
抗原
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