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14-3-3 theta 抗体 (AA 20-225)
YWHAQ
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
14-3-3 theta抗体详情
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抗原
See all 14-3-3 theta (YWHAQ) 抗体
14-3-3 theta (YWHAQ)
抗原表位
All epitopes for 14-3-3 theta 抗体
AA 20-225
适用
All reactivities for 14-3-3 theta 抗体
人
宿主
All hosts for 14-3-3 theta 抗体
兔
克隆类型
All clonalities for 14-3-3 theta 抗体
多克隆
标记
All conjugates for 14-3-3 theta 抗体
This 14-3-3 theta antibody is un-conjugated
应用范围
All applications for 14-3-3 theta 抗体
Western Blotting (WB)
纯化方法
Protein A Chromatography
免疫原
A partial length recombinant 14-3-3 protein (amino acids 20-225) was used as the immunogen for this antibody.
亚型
IgG
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Discover our top product YWHAQ Primary Antibody
Alternatives
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使用细节
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应用备注
WB: 2-4 μg/mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
PBS containing 0.05 % BSA, PH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
14-3-3 theta目标详情
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抗原
14-3-3 theta (YWHAQ)
别名
YWHAQ (YWHAQ 产品 )
别名
14-3-3 antibody, 14-3-3t antibody, 1c5 antibody, hs1 antibody, 1C5 antibody, HS1 antibody, 2700028P07Rik antibody, AA409740 antibody, AU021156 antibody, R74690 antibody, ywhaq antibody, ywhaq2 antibody, wu:fa91b01 antibody, wu:fb02e12 antibody, wu:fb36f06 antibody, wu:fk86h02 antibody, ywhaq1 antibody, ywhaz antibody, zgc:55499 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a antibody, 14-3-3 protein theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b antibody, YWHAQ antibody, ywhaq antibody, Ywhaq antibody, ywhaq.S antibody, ywhaqa antibody, ywhaqb antibody
背景
YWHAQ, also known as 14-3-3 tau (14-3-3tau) is a a phosphoserine-binding protein and a member of the 14-3-3 family of proteins. The 14-3-3 family members are dimeric phosphoserine/ phosphothreonine-binding proteins, which are involved in a very diverse spectrum of signaling pathways. YWHAQ plays a critical role in the regulation of E2F1 stability. It binds to Ser31-phosphorylated E2F1 and inhibits the ubiquitination of E2F1 during DNA damage. The binding of YWHAQ to E2F1 interferes with the function of an E31 ligase and therefore inhibits the ubiquitination and degradation of E2F1. This interaction is required for the expression and induction of several E2F1 apoptotic target genes as well as apoptosis during DNA damage.
分子量
29 kDa
基因ID
10971
UniProt
P27348
途径
Apoptosis , Myometrial Relaxation and Contraction
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