14-3-3 theta 抗体 (AA 20-225)
Quick Overview for 14-3-3 theta 抗体 (AA 20-225) (ABIN5027003)
抗原
See all 14-3-3 theta (YWHAQ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-225
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant 14-3-3 protein (amino acids 20-225) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-14-3-3 theta (YWHAQ) (AA 1-245) antibody
YWHAQ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) (AA 1-245) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 5C4E7 unconjugated
anti-14-3-3 theta (YWHAQ) (Center) antibodyYWHAQ 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) antibodyYWHAQ 适用: 人, 小鼠, 大鼠 WB, IF (cc) 宿主: 兔 Monoclonal 5G1 unconjugated
anti-14-3-3 theta (YWHAQ) (AA 1-245) antibodyYWHAQ 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT1A1 unconjugated
anti-14-3-3 theta (YWHAQ) (C-Term) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) antibodyYWHAQ 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-14-3-3 theta (YWHAQ) (N-Term) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 兔, 非洲爪蟾, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) (C-Term) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 兔, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) (Center) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 14-3-3 theta (YWHAQ)
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别名
- YWHAQ
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背景
- YWHAQ, also known as 14-3-3 tau (14-3-3tau) is a a phosphoserine-binding protein and a member of the 14-3-3 family of proteins. The 14-3-3 family members are dimeric phosphoserine/ phosphothreonine-binding proteins, which are involved in a very diverse spectrum of signaling pathways. YWHAQ plays a critical role in the regulation of E2F1 stability. It binds to Ser31-phosphorylated E2F1 and inhibits the ubiquitination of E2F1 during DNA damage. The binding of YWHAQ to E2F1 interferes with the function of an E31 ligase and therefore inhibits the ubiquitination and degradation of E2F1. This interaction is required for the expression and induction of several E2F1 apoptotic target genes as well as apoptosis during DNA damage.
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分子量
- 29 kDa
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基因ID
- 10971
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UniProt
- P27348
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途径
- Apoptosis, Myometrial Relaxation and Contraction
抗原
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