Elastase 抗体
适用: 哺乳动物
ELISA, WB, IHC, AGG
宿主: 小鸡
Polyclonal
unconjugated
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- 抗原 See all Elastase 抗体
- Elastase
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适用
- 哺乳动物
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This Elastase antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Agglutination (AGG)
- 产品特性
- IgY-antibody
- 纯化方法
- Precipitation with ammoniumsulfate , dialyse and fitration
- 免疫原
- raw, native protein
- 亚型
- IgY
- Top Product
- Discover our top product Elastase Primary Antibody
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- 应用备注
- Perform a chessboard titation before the first application
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, 0.1 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- Elastase
- Abstract
- Elastase 产品
- 背景
- Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.
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