ZNF536 抗体 (N-Term)
This anti-ZNF536 antibody is a 兔 多克隆 antibody detecting ZNF536 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for ZNF536 抗体 (N-Term) (ABIN501163)
抗原
See all ZNF536 抗体
ZNF536
(Zinc Finger Protein 536 (ZNF536))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This ZNF536 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Affinity chromatography
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免疫原
- 16 amino acid peptide from near the amino terminus of human ZNF536
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亚型
- IgG
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anti-Zinc Finger Protein 536 (ZNF536) (AA 203-231), (N-Term) antibody
ZNF536 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28209 unconjugated
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应用备注
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ELISA. Western blot at 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- ZNF536 (Zinc Finger Protein 536 (ZNF536))
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别名
- ZNF536
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背景
- ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and b-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.Synonyms: KIAA0390, Zinc finger protein 532, Zinc finger protein 532
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基因ID
- 9745
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NCBI登录号
- NP_055532
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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