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ZNF536 抗体 (N-Term)

ZNF536 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991232
发货至: 中国
  • 抗原 See all ZNF536 抗体
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    抗原表位
    • 8
    • 8
    • 6
    AA 30-80, N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This ZNF536 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 12
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    ZNF536 Antibody is affinity chromatography purified via peptide column.
    免疫原
    ZNF536 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ZNF536. The immunogen is located within amino acids 30 - 80 of ZNF536.
    亚型
    IgG
    Top Product
    Discover our top product ZNF536 Primary Antibody
  • 应用备注
    ZNF536 antibody can be used for detection of ZNF536 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ZNF536 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ZNF536 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    别名
    ZNF536 (ZNF536 产品)
    别名
    9630010P11Rik antibody, Znf536 antibody, mKIAA0390 antibody, RGD1563363 antibody, zinc finger protein 536 antibody, ZNF536 antibody, Zfp536 antibody
    背景
    ZNF536 Antibody: ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
    基因ID
    9745
    NCBI登录号
    NP_055532
    UniProt
    O15090
    途径
    Retinoic Acid Receptor Signaling Pathway
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