WNT10A 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for WNT10A 抗体 (C-Term) (ABIN501122)
抗原
See all WNT10A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects WNT10A. Despite the high homology of Wnt10a to Wnt10b, this Wnt10a antibody will not cross-react with Wnt10b.
-
交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Affinity chromatography
-
免疫原
- Wnt10a antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Wnt10a.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunhistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))
-
别名
- WNT10A
-
背景
- Wnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia.Synonyms: Protein Wnt-10a
-
基因ID
- 80326
-
UniProt
- Q9GZT5
-
途径
- WNT signaling
抗原
-