UNG 抗体 (N-Term)
Quick Overview for UNG 抗体 (N-Term) (ABIN501108)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Uracil-DNA glycosylase (UNG) at N-term. The antibody will not cross-react with UNG2.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- UNG1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human UNG1.
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亚型
- IgG
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anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibody
UNG 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) antibodyUNG 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 114-224) antibodyUNG 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (Internal Region) antibodyUNG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 281-298) antibodyUNG 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-100) antibodyUNG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibodyUNG 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal k1C12 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (N-Term) antibodyUNG 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- UNG (Uracil-DNA Glycosylase (UNG))
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背景
- The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders in an age-dependent manner.Synonyms: DGU, UDG, UNG1, UNG15
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基因ID
- 7374
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NCBI登录号
- NP_003353
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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