UNC93B1 抗体 (N-Term)
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Quick Overview for UNC93B1 抗体 (N-Term) (ABIN501104)
抗原
See all UNC93B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Unc93b. The antibody will not cross-react with Unc93a.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- Unc93b antibody was raised against a 19 amino acid peptide from near the amino terminus of human Unc93b.
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亚型
- IgG
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anti-Unc-93 Homolog B1 (UNC93B1) (AA 451-550) antibody
UNC93B1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 450-550) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 83-135) antibodyUNC93B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 500-550) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 61-110) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 300-597) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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别名
- UNC93B1
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背景
- The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C. elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling. Unlike Unc93a, another homolog of the C. elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9, the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction. Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indicating that Unc93b plays an important role in innate immunity. Multiple isoforms of Unc93a are known to exist.Synonyms: Protein unc-93 homolog B1, UNC-93B, UNC93
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基因ID
- 81622
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NCBI登录号
- NP_112192
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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