UBE2N 抗体 (C-Term)
Quick Overview for UBE2N 抗体 (C-Term) (ABIN501096)
抗原
See all UBE2N 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects UBE2N / BLU.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Ion exchange chromatography
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免疫原
- UBC13 antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human UBC13.
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) antibody
UBE2N 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1-D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 41-74) antibodyUBE2N 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB49505 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 56-152) antibodyUBE2N 适用: 大鼠, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 20-138) antibodyUBE2N 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C11-G11 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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背景
- Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway (1). It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway (reviewed in 2). Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors (2,3). Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family (4-6). The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation (5).Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N
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基因ID
- 7334
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
抗原
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