TWEAK 抗体
Quick Overview for TWEAK 抗体 (ABIN501094)
抗原
See all TWEAK (TNFSF12) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects TWEAK / TNFSF12.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Peptide Affinity Chromatography
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免疫原
- Recombinant Human TWEAK.
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亚型
- IgG
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (N-Term) antibody
TNFSF12 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 49-134) antibodyTNFSF12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H3 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 43-149) antibodyTNFSF12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 42-123) antibodyTNFSF12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (Pro73) antibodyTNFSF12 适用: 人, 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 94-249) antibodyTNFSF12 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM140 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 65-247) antibodyTNFSF12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 53-249) antibodyTNFSF12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 41-90) antibodyTNFSF12 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) antibodyTNFSF12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
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别名
- TWEAK / TNFSF12
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背景
- TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane (1,2). TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis (3), induction of inflammatory cytokines (4), in addition to stimulation of apoptosis (5). The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains (1). Despite its predicted molecular weight of 27 kDa, TWEAK may migrate at aberrant positions in SDS-PAGE.Synonyms: APO3 ligand, APO3L, DR3LG, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12
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基因ID
- 8742
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NCBI登录号
- NP_003800
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途径
- Apoptosis
抗原
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