Sphingomyelin Synthase 1 抗体 (AA 331-413) (AbBy Fluor® 680)
Quick Overview for Sphingomyelin Synthase 1 抗体 (AA 331-413) (AbBy Fluor® 680) (ABIN5010925)
抗原
See all Sphingomyelin Synthase 1 (SGMS1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 331-413
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1
-
亚型
- IgG
-
-
anti-Sphingomyelin Synthase 1 (SGMS1) (AA 331-413) antibody
SGMS1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) (AA 48-137) antibodySGMS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) (AA 1-134) antibodySGMS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) antibodySGMS1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) (AA 144-193) antibodySGMS1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) (AA 24-53), (N-Term) antibodySGMS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32319 unconjugated
anti-Sphingomyelin Synthase 1 (SGMS1) (Middle Region) antibodySGMS1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- Sphingomyelin Synthase 1 (SGMS1)
-
别名
- Sphingomyelin Synthase 1
-
背景
-
Synonyms: MOB, MOB1, SMS1, TMEM23, hmob33, Phosphatidylcholine:ceramide cholinephosphotransferase 1, Medulla oblongata-derived protein, Protein Mob, Sphingomyelin synthase 1, Transmembrane protein 23, SGMS1
Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
-
基因ID
- 259230
-
UniProt
- Q86VZ5
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-
