SKP2 抗体 (AA 351-424) (AbBy Fluor® 680)
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北京 101111
Quick Overview for SKP2 抗体 (AA 351-424) (AbBy Fluor® 680) (ABIN5010586)
抗原
See all SKP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-424
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Skp2
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亚型
- IgG
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anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 351-424) antibody
SKP2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-100) antibodySKP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (C-Term) antibodySKP2 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 221-425) antibodySKP2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 43-397) antibodySKP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 6D4 unconjugated Recombinant Antibody
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 适用: 人 ELISA, IF, FACS 宿主: 兔 Monoclonal 3C11 unconjugated Recombinant Antibody
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
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别名
- SKP2
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背景
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Synonyms: p45, FBL1, FLB1, FBXL1, S-phase kinase-associated protein 2, Cyclin-A/CDK2-associated protein p45, F-box protein Skp2, F-box/LRR-repeat protein 1, p45skp2, SKP2
Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.
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基因ID
- 6502
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UniProt
- Q13309
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途径
- Mitotic G1-G1/S Phases
抗原
-
