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TOLLIP 抗体 (C-Term)

This 兔 多克隆 anti-TOLLIP antibody specifically detects TOLLIP in WB, IF 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN501006
发货至: 中国
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Quick Overview for TOLLIP 抗体 (C-Term) (ABIN501006)

抗原

See all TOLLIP 抗体
TOLLIP (Toll Interacting Protein (TOLLIP))

适用

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人, 小鼠, 大鼠

宿主

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  • 2

克隆类型

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多克隆

标记

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This TOLLIP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects TOLLIP at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    TOLLIP antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human TOLLIP.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month.
  • 抗原

    TOLLIP (Toll Interacting Protein (TOLLIP))

    别名

    TOLLIP

    背景

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.Synonyms: Toll-interacting protein

    基因ID

    54472
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