TOLLIP 抗体 (C-Term)
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Quick Overview for TOLLIP 抗体 (C-Term) (ABIN501006)
抗原
See all TOLLIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TOLLIP at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- TOLLIP antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human TOLLIP.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month.
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- TOLLIP (Toll Interacting Protein (TOLLIP))
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别名
- TOLLIP
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背景
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.Synonyms: Toll-interacting protein
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基因ID
- 54472
抗原
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