TNFAIP3 抗体 (C-Term)
(1 reference)Quick Overview for TNFAIP3 抗体 (C-Term) (ABIN500994)
抗原
See all TNFAIP3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects TNFAIP3 at C-term.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- TNFAIP3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFAIP3.
-
亚型
- IgG
-
-
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 1-190) antibody
TNFAIP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (Internal Region) antibodyTNFAIP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 51-150) antibodyTNFAIP3 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 1-300) antibodyTNFAIP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 97-183) antibodyTNFAIP3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibodyTNFAIP3 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 59A426 unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 1-190) antibodyTNFAIP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 321-370) antibodyTNFAIP3 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL. Immunohistocheistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
-
: "The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 3, pp. 1100-10, (2016) (PubMed).
-
: "The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 3, pp. 1100-10, (2016) (PubMed).
-
- TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
-
别名
- TNFAIP3
-
背景
- TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kB-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.Synonyms: OTU domain-containing protein 7C, OTUD7C, Putative DNA-binding protein A20, Tumor necrosis factor alpha-induced protein 3, Zinc finger protein A20
-
基因ID
- 7128
-
NCBI登录号
- NP_006281
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response
抗原
-
