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TLR9 抗体 (Center)

This anti-TLR9 antibody is a 兔 多克隆 antibody detecting TLR9 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN500968
发货至: 中国

Quick Overview for TLR9 抗体 (Center) (ABIN500968)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody detects CD289 / TLR9 at center.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    TLR9 antibody was raised against a peptide corresponding to 15 amino acids near the center of human TLR9.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Yu, Bai, Zhang, Wang, Yu: "Repetitive extragenic palindromic DNA sequences from Brucella melitensis stimulate Toll-like receptor 9 signaling in macrophages." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 271-276, (2017) (PubMed).

  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    别名

    CD289 / TLR9

    背景

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences (3) and are localized in intracellular acidic compartments such as the phagolysosome (4). Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection (5), TLR9 is strictly dependent on MyD88 (3).Synonyms: Toll-like receptor 9, UNQ5798/PRO19605

    基因ID

    54106

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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