TLR7 抗体 (Middle Region)
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北京 101111
Quick Overview for TLR7 抗体 (Middle Region) (ABIN500962)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects TLR7 at Center.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Ion exchange chromatography
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免疫原
- TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the middle of mouse TLR7.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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背景
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome (6) and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus (7). Activation of TLR7 by VSV results in stimulation of the immune response including IFN? secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7
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基因ID
- 170743
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NCBI登录号
- NP_573474
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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