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TLR5 抗体 (C-Term)

This anti-TLR5 antibody is a 兔 多克隆 antibody detecting TLR5 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500956
发货至: 中国

Quick Overview for TLR5 抗体 (C-Term) (ABIN500956)

抗原

See all TLR5 抗体
TLR5 (Toll-Like Receptor 5 (TLR5))

适用

  • 108
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  • 1
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人, 小鼠

宿主

  • 97
  • 20
  • 3

克隆类型

  • 91
  • 29
多克隆

标记

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  • 5
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  • 1
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This TLR5 antibody is un-conjugated

应用范围

  • 95
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  • 12
  • 12
  • 6
  • 3
  • 3
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 13
    • 8
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    • 5
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    C-Term

    特异性

    This antibody detects TLR5 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    TLR5 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TLR5 (Toll-Like Receptor 5 (TLR5))

    别名

    TLR5

    背景

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-κB, leading to the activation of TNF-? and other cytokines (4). A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires' disease and demonstrates the importance of TLR5 in the innate immune response (5).Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3

    基因ID

    7100

    NCBI登录号

    NP_003259

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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