TLR3 抗体 (C-Term)
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Quick Overview for TLR3 抗体 (C-Term) (ABIN500948)
抗原
See all TLR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects CD283 / TLR3 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Ion exchange chromatography
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免疫原
- TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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别名
- CD283 / TLR3
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背景
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection (4). Recently it has been shown to recognize viruses such as Influenza A (5) and West Nile Virus and can mediate entry of at least West Nile Virus (6).Synonyms: Toll-like receptor 3
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基因ID
- 7098
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UniProt
- O15455
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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