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TLR3 抗体 (C-Term)

This anti-TLR3 antibody is a 兔 多克隆 antibody detecting TLR3 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500948
发货至: 中国

Quick Overview for TLR3 抗体 (C-Term) (ABIN500948)

抗原

See all TLR3 抗体
TLR3 (Toll-Like Receptor 3 (TLR3))

适用

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人, 小鼠

宿主

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克隆类型

  • 92
  • 35
多克隆

标记

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This TLR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects CD283 / TLR3 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Ion exchange chromatography

    免疫原

    TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 to 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TLR3 (Toll-Like Receptor 3 (TLR3))

    别名

    CD283 / TLR3

    背景

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection (4). Recently it has been shown to recognize viruses such as Influenza A (5) and West Nile Virus and can mediate entry of at least West Nile Virus (6).Synonyms: Toll-like receptor 3

    基因ID

    7098

    UniProt

    O15455

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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