TLR1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for TLR1 抗体 (N-Term) (ABIN500936)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
交叉反应 (详细)
- Species reactivity (tested):Human, mouse
-
纯化方法
- Ion exchange chromatography
-
免疫原
- TLR1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TLR1.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 1 to 2 μg/mL. Immunohoistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- TLR1 (Toll-Like Receptor 1 (TLR1))
-
别名
- CD281 / TLR1
-
背景
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7).Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
-