TICAM2 抗体 (C-Term)
(2 references)Quick Overview for TICAM2 抗体 (C-Term) (ABIN500931)
抗原
See all TICAM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TICAM2 / TRAM.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Ion exchange chromatography
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免疫原
- TIRP antibody was raised against a peptide corresponding to amino acids near the C- terminus of human TIRP.
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亚型
- IgG
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anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (C-Term) antibody
TICAM2 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 150-200) antibodyTICAM2 适用: 人, 小鼠, 大鼠, 猴, Cow, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) antibodyTICAM2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 34-241) antibodyTICAM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 2 μg/mL. Immunohistochemistry on parffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway." in: Stem cells international, Vol. 2017, pp. 5841814, (2017) (PubMed).
: "Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway." in: PLoS pathogens, Vol. 11, Issue 5, pp. e1004881, (2016) (PubMed).
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: "Electroacupuncture Improved Hippocampal Neurogenesis following Traumatic Brain Injury in Mice through Inhibition of TLR4 Signaling Pathway." in: Stem cells international, Vol. 2017, pp. 5841814, (2017) (PubMed).
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- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
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别名
- TICAM2 / TRAM
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背景
- TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (5). Expression of TIRP appears to be essential for TLR4 signalling (6).Synonyms: Putative NF-kappa-B-activating protein 502, TICAM-2, TIR domain-containing adapter molecule 2, TIRAP3, TIRP, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein
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基因ID
- 353376
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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