ARHGEF17 抗体 (Center)
This anti-ARHGEF17 antibody is a 兔 多克隆 antibody detecting ARHGEF17 in WB, IHC (p) 和 EIA. Suitable for 人.
Quick Overview for ARHGEF17 抗体 (Center) (ABIN500893)
抗原
See all ARHGEF17 抗体
ARHGEF17
(rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
适用
人
宿主
兔
克隆类型
多克隆
标记
This ARHGEF17 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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特异性
- This antibody detects ARHGEF17 / TEM4 at center.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17) (C-Term) antibody
ARHGEF17 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
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别名
- ARHGEF17 / TEM4
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背景
- Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.Synonyms: 164 kDa Rho-specific guanine-nucleotide exchange factor, KIAA0337, Rho guanine nucleotide exchange factor 17, Tumor endothelial marker 4, p164-RhoGEF, p164RhoGEF
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基因ID
- 9828
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UniProt
- Q96PE2
抗原
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