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ARHGEF17 抗体 (AA 910-960)

ARHGEF17 适用: 人 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990812
发货至: 中国
  • 抗原 See all ARHGEF17 抗体
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    AA 910-960
    适用
    • 11
    • 9
    宿主
    • 11
    克隆类型
    • 11
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF17 antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    TEM4 Antibody is affinity chromatography purified via peptide column.
    免疫原
    TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4. The immunogen is located within amino acids 910 - 960 of TEM4.
    亚型
    IgG
    Top Product
    Discover our top product ARHGEF17 Primary Antibody
  • 应用备注
    TEM4 antibody can be used for detection of TEM4 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TEM4 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TEM4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    别名
    TEM4 (ARHGEF17 产品)
    别名
    P164RHOGEF antibody, TEM4 antibody, p164-RhoGEF antibody, 8030463K16 antibody, AI428794 antibody, AW558066 antibody, BC035332 antibody, mKIAA0337 antibody, Rho guanine nucleotide exchange factor 17 antibody, Rho guanine nucleotide exchange factor (GEF) 17 antibody, ARHGEF17 antibody, Arhgef17 antibody
    背景
    TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
    分子量
    Predicted: 220 kDa

    Observed: 200 kDa
    基因ID
    9828
    UniProt
    Q96PE2
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