IL27 Receptor alpha 抗体 (N-Term)
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北京 101111
Quick Overview for IL27 Receptor alpha 抗体 (N-Term) (ABIN500875)
抗原
See all IL27 Receptor alpha (IL27RA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects TCCR / IL27RA at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor.
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亚型
- IgG
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anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 21-120) antibody
IL27RA 适用: 人, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 33-283) antibodyIL27RA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 93-273) antibodyIL27RA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 117-350) antibodyIL27RA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 569-602), (C-Term) antibodyIL27RA 适用: 人 WB 宿主: 兔 Polyclonal RB30673 unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 33-132) antibodyIL27RA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G9 unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (AA 123-343) antibodyIL27RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 27 Receptor, alpha (IL27RA) (C-Term) antibodyIL27RA 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. An approximately 70 kDa band can be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
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别名
- TCCR / IL27RA
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背景
- Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.Synonyms: CRL1, IL-27R-alpha, Interleukin-27 receptor subunit alpha, T-cell cytokine receptor type 1, UNQ296/PRO336, WSX-1, WSX1
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基因ID
- 9466
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NCBI登录号
- NP_004834
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途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
抗原
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