STK39 抗体 (Center)
Quick Overview for STK39 抗体 (Center) (ABIN500835)
抗原
See all STK39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects STK39 / SPAK at center.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Stk39 antibody was raised against a 18 amino acid peptide from near the center of human Stk39.
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亚型
- IgG
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anti-serine threonine Kinase 39 (STK39) antibody
STK39 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (AA 346-376) antibodySTK39 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03418 unconjugated
anti-serine threonine Kinase 39 (STK39) (Internal Region) antibodyVerified STK39 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser325) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser311) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (AA 63-545) antibodySTK39 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer311) antibodySTK39 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) antibodySTK39 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 4E3 unconjugated
anti-serine threonine Kinase 39 (STK39) (C-Term) antibodySTK39 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer325) antibodySTK39 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- STK39 (serine threonine Kinase 39 (STK39))
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别名
- STK39 / SPAK
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背景
- The serine/threonine kinase Stk39 belongs to the STE20 family, a group of kinases that are known to interact with inflammation-related kinases (such as p38, JNK, NKCC1, PKC-theta, WNK and MLCK), and with transcription factor AP-1. The STE 20 family is involved in diverse biological phenomena, including cell differentiation, cell transformation/ proliferation, cytoskeleton rearrangement, and the regulation of ion transporters. STK39 contains an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain and is abundantly expressed in the brain. STK39 is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled co-transporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Recent studies show that STK39 tend to be a novel candidate gene for autism and hypertension.Synonyms: DCHT, STE20/SPS1-related proline-alanine-rich protein kinase, Serine/threonine-protein kinase 39, Ste-20-related kinase
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基因ID
- 27347
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NCBI登录号
- NP_037365
抗原
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