Stim2 抗体 (Center)
Our Local Distributor
北京 101111
Quick Overview for Stim2 抗体 (Center) (ABIN500831)
抗原
See all Stim2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detects STIM2 at center. It is predicted to have no cross-reactivity to STIM1.
-
交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- STIM2 antibody was raised against a 17 amino acid peptide from near the center of human STIM2.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- Stim2 (Stromal Interaction Molecule 2 (Stim2))
-
别名
- STIM2
-
背景
- In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.Synonyms: KIAA1482, Stromal interaction molecule 2
-
基因ID
- 57620
-
NCBI登录号
- NP_065911
-
途径
- TCR Signaling, BCR Signaling
抗原
-