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Stim2 抗体 (Center)

This anti-Stim2 antibody is a 兔 多克隆 antibody detecting Stim2 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500831
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Stim2 抗体 (Center) (ABIN500831)

抗原

See all Stim2 抗体
Stim2 (Stromal Interaction Molecule 2 (Stim2))

适用

  • 35
  • 13
  • 9
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 2
  • 1

克隆类型

  • 35
多克隆

标记

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  • 1
This Stim2 antibody is un-conjugated

应用范围

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  • 24
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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 6
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    • 2
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    • 1
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    • 1
    • 1
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    Center

    特异性

    This antibody detects STIM2 at center. It is predicted to have no cross-reactivity to STIM1.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    STIM2 antibody was raised against a 17 amino acid peptide from near the center of human STIM2.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Stim2 (Stromal Interaction Molecule 2 (Stim2))

    别名

    STIM2

    背景

    In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.Synonyms: KIAA1482, Stromal interaction molecule 2

    基因ID

    57620

    NCBI登录号

    NP_065911

    途径

    TCR Signaling, BCR Signaling
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