SIRT2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for SIRT2 抗体 (N-Term) (ABIN500726)
抗原
See all SIRT2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects SIRT2 / SIR2 at N-term.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromtography
-
免疫原
- SIRT2 antibody was raised against a 17 amino acid peptide near the amino terminus of the human SIRT2.
-
亚型
- IgG
-
-
anti-Sirtuin 2 (SIRT2) (AA 288-389) antibody
SIRT2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 128-227) antibodySIRT2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sirtuin 2 (SIRT2) (AA 165-187), (Middle Region) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 28-303) antibodySIRT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 1D4-H11-H11 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 275-389) antibodySIRT2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5H11H9 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 2.5 - 5 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- SIRT2 (Sirtuin 2 (SIRT2))
-
别名
- SIRT2 / SIR2
-
背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions. Multiple isoforms of ATG16 are known to exist.Synonyms: NAD-dependent deacetylase sirtuin-2, SIR2-like protein 2, SIR2L, SIR2L2, SIRT-2, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae), sirtuin 2, sirtuin type 2, sirtuin-2
-
基因ID
- 22933
-
NCBI登录号
- NP_036369
-
UniProt
- Q8IXJ6
抗原
-
